Drug intelligence / Profile preview

6-phenyl[5H]pyrrolo[2,3-b]pyrazine

Development stage
Unknown
Modality
Small Molecules
01

Overview

**6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE** is a heterocyclic organic compound characterized by fused pyrrole and pyrazine rings with a phenyl group at the sixth position. It belongs to the class of phenylpyrroles and is considered an experimental small molecule. The compound has been investigated for its potential antitumor or anticancer properties and has shown inhibitory activity against cyclin-dependent kinase 5 (CDK5) with an IC50 of approximately 200 nM. Its unique structure makes it a candidate for further exploration in medicinal chemistry as well as organic electronics. There are no approved indications or clinical trials beyond preclinical/experimental stages.[1][2][8]

Other names
5H-pyrrolo[2,3-b]pyrazine, 6-phenyl-6-Phenyl-5H-pyrrolo[2,3-b]pyrazin6-phényl-5H-pyrrolo[2,3-b]pyrazineCAS 78605-10-4CAS78605-10-4CAS-78605-10-4
02

Targets

CDK5 (Cyclin-dependent kinase 5)

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